Gabapentin is a little different than other anticonvulsants. Unlike benzodiazepines and barbiturates, gabapentin does not directly target the GABA receptor. Instead, it acts on multiple pathways in the brain. One of its main actions involves binding to the α2δ subunit of voltage-dependent calcium channels. This binding blocks calcium from entering neurons, ultimately reducing the release of neurotransmitters. Interestingly, it also binds to a specific subunit (α2δ) of nerve cells which stimulates the production of GABA, another neurotransmitter that has calming effects. Gabapentin also interacts with other receptors on nerve cells such as the μ-opioid receptor and nicotinic acetylcholine receptors, although these interactions are not fully understood. These interactions likely contribute to gabapentin's ability to control seizures and pain, making it a valuable medication for certain neurological conditions.
- Managing neuropathic pain
- Treating seizures in epilepsy
- Reducing anxiety symptoms
- Alleviating restless legs syndrome
Composition
Each capsule contains:
- Gabapentin: 300 mg
Suggested Usage
- Use only as directed by the physician.
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