Description
Description
Metformin 1000mg primarily works by reducing glucose production in the liver and enhancing insulin sensitivity in peripheral tissues. It inhibits the mitochondrial respiratory chain complex I, leading to reduced ATP production and decreased hepatic glucose output. Additionally, metformin improves insulin-mediated glucose uptake in skeletal muscle and adipose tissue. On the other hand, Sitagliptin 50mg, a dipeptidyl peptidase-4 (DPP-4) inhibitor, acts by blocking the breakdown of incretin hormones such as GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide). This inhibition results in elevated levels of these hormones, which stimulate insulin secretion in a glucose-dependent manner, suppress glucagon secretion, and slow gastric emptying, ultimately leading to improved glycemic control.
- Used for controlling blood sugar levels in type 2 diabetes.
- Used to enhance insulin sensitivity and reduce glucose production in the liver.
- Used to improve glycemic control by regulating blood sugar levels.
- Used to lower the risk of cardiovascular events in diabetic patients.
Composition
Each film coated tablet contains:
- Metformin: 1000 mg
- Sitagliptin: 50 mg
Suggested Usage
- Take as per doctor's prescription.
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